DeePuff

    No image available

    Buffalo Bill

    Submit a photo!
    sativa
    16%
    THC
    0%
    CBD
    Medium
    Potency

    Sign in to submit photos

    sativa Dominant

    Buffalo Bill

    0.0
    0 reviews
    Needs review
    Updated Feb 2026
    Potency
    Medium
    Top Terpene
    Caryophyllene
    Primary Effect
    Happy
    Vibe Match
    Chill Evening
    Potency Cue
    Easy pace
    CalmEnergy
    BodyHead
    DeePuff Intelligence

    Read the ride before you spark it

    High Forecast
    Onset
    Bright lift
    Peak
    Creative / social
    Come-down
    Sleepy coast
    Crash Risk
    Low
    Don't pick this if
    Dry mouth hits you hard
    Dry eyes are a deal-breaker
    Compatibility
    Creative work90%
    Evening chill75%
    Sleep support35%
    Social mode85%
    Best Time Dial
    MorningDayEveningNight
    Best around: Day
    THC
    profiled
    Terpenes
    mapped
    Effects
    community-weighted
    Confidence
    medium
    DeePuff Pick Reason

    Buffalo Bill earns its DeePuff fit from 16% THC, a chill evening profile led by Caryophyllene, and effects that lean brighter and more active.

    Stack Guidance
    Stacks with
    Citrus terpene strains for lift
    Light body strains for balance
    Avoid stacking
    Very sedating indicas if you need momentum
    Unknown edibles until you know tolerance

    This is a fantastic strain! Great taste of sweet pine with a little earthy undertone. The effects were outstanding! Immediately got a happy, euphoric, and tingly head high. The body high crept up on me. Even though it was relaxing, I felt Buffalo Bill was functional. Great for some daytime pain relief. It was pretty uplifting. So, was good for depression too. Doc and Yeti grew this amazingly crystalized, and tasty cross of William's Wonder and Killer Chem. I love those guys! They really grow some great weed. I've tried many of their strains and all have been top shelf stuff.

    Spot something off? Send a sourced correction, or let DeePuff re-check public reference signals for consistency.

    Buffalo Bill Statistics

    THC Range

    8–23%

    CBD Content

    0%

    Dominant Terpenes
    Caryophyllene (0.05% - 2.0%)Limonene (0.1% - 2.5%)Myrcene (0.1% - 3.0%)
    Reported Medical Uses
    StressAnxietyDepressionPain
    Best Time
    afternoon

    Effectsref

    HappyEuphoricUpliftedTinglyArousedCalmBlissfulBody high

    Possible Side Effects

    Dry MouthDry EyesDizzyHeadache

    Science Snapshot

    74
    Entourage
    Moderate
    Complexity
    5
    Aroma Families
    Top synergy: THC × Myrcene: Enhanced sedation & body high
    THC:CBD → 16:<1|3 terpenes identified

    Flavor Profile

    EarthySweetPineWoodyLavenderBerryGrapeMint

    Medical Uses

    StressAnxietyDepressionPainMuscle SpasmsInsomniaInflammationFibromyalgia

    * Consult a medical professional for personalized advice

    Potency Analysis

    THC16%
    CBD0%
    Good for most users

    Your starting dose

    general estimate

    Start with 6 small inhalations (or ~9 mg edible). Buffalo Bill matches your typical strain (×0.9).

    Tolerance read: 4/10Sign in to personalize →

    THC-Dominant Recreational

    THC only

    Classic recreational profile. Maximum psychoactive load, minimal CBD modulation.

    Most modern dispensary flower (ElSohly 2016 cannabinoid trend study).

    Actual Delivered Dose

    Buffalo Bill is 16% THC, but combustion + first-pass loss eat most of it. Here's what reaches your bloodstream.

    Total THC in dose: 48 mg

    Joint / Blunt
    13 mg27%
    Bong
    19.2 mg40%
    Dry-Herb Vape
    31.2 mg65%
    Dab / Concentrate
    33.6 mg70%
    Edible
    9.6 mg20%
    Sublingual / Oil
    14.4 mg30%
    Sources

    Joint / Blunt: Combustion + sidestream loss; ~63–73% destroyed (Pomahacova 2009).

    Bong: Cooler combustion, less sidestream; ~50–60% retained.

    Dry-Herb Vape: Volcano studies show ~55–80% delivery at 180–210°C (Hazekamp 2006).

    Dab / Concentrate: Pre-decarbed extract; quartz-banger 500°F (Raber 2015).

    Edible: High first-pass hepatic loss; 4–20% bioavailability (Lucas 2018).

    Sublingual / Oil: Bypasses some first-pass; 13–35% bioavailable.

    Terpene Profile

    The aromatic compounds that define this strain's unique characteristics and effects

    Buffalo BillTop Terpene🌶️ Caryophyllene🌶️ Caryophyllene🍋 Limonene🌿 Myrcene

    What are Terpenes?

    Terpenes are aromatic compounds found in cannabis that contribute to each strain's unique smell, taste, and effects. They work synergistically with cannabinoids in what's known as the "entourage effect" to enhance or modify the overall experience.

    Dominant Terpenes in Buffalo Bill

    Caryophyllene Limonene Myrcene
    Are you the breeder? Promote this strain →